From Curiosity to Confidence: My TRIP into Biomedical Research by Nuha Maryam

It still thrills me that I had the opportunity to be part of the 2025 Teen Research Internship Program (TRIP) offered by Fox Chase Cancer Center, Temple Health. The past two and a half months flew by as I settled into a routine—spending every Saturday morning at William Tennent High School. And now, as the program ends, there is a mixed feeling of sadness, gratitude, and excitement. I’m sad to see the end of a great time I had during the program learning scientific concepts and developing scientific aptitude. I’m grateful for the chance to be part of like-minded peers and incredibly supportive mentors. And I’m excited to apply all that I learned to fulfill my goals.

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The project topic I selected was derived from my interest in translational medicine that is the bridge between basic research and clinical application. I explored: “Can Curcumin Ameliorate the Detrimental Effects of Sleep Deprivation?” This study aimed to examine the potential of curcumin-based therapies to improve health outcomes. I was so excited to have the chance to work hands-on with Drosophila melanogaster that I always knew as a well-known model organism in biomedical research due to its genetic and physiological similarities to humans. I conducted both developmental and locomotion assays—including Percent Eclosion, Negative Geotaxis, and Larval Locomotion Assays—to study the drug's impact under stress conditions. My studies highlight the promising use of curcumin for therapeutic applications for various diseases, however, in-depth study is needed to explore further.

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I consider myself a passionate STEM enthusiast, interested in biomedical research and laser-focused on a future in healthcare. Basic research experience is important to lay the groundwork for evidence-based medicine in patient care. The fundamental understanding I’ve gained from TRIP is an invaluable addition to my scientific toolbox. I loved the vibrant and supportive environment during the program that not only provided real-world experience beyond the classroom, but it also boosted my confidence. Thanks to my amazing mentors: Dr. Purdy, Dr. Austria, Dr. Valdes, and Mr. Cozzone! It was a great opportunity to make some new friends too.
TRIP was a transformative experience. I leave this program with new knowledge, meaningful connections, and an even stronger drive to pursue biomedical research and clinical impact.